Five minutes later you're interrupted again by yells for help with something. You get up from your desk to deal with it. By the time you get back your drink is cold and you've lost your train of thought and you have to start over. Before you know it, an hour or more has gone by and you've gotten very little work done.
Short of retreating into the farthest room of the house and locking the door, what can one do?
Lay down the rules. Inform the other family members that you need a certain amount of time for work, and you're not to be bothered unless it's a real emergency like flood, fire, or burglary.
Get someone else to watch the kids. If the kids in the household aren't old enough to keep themselves occupied, consider hiring a sitter for them during the times you need to work.
Set aside a block of time when the house is quiet. Whether early in the morning or late at night, this can minimize the chances of someone walking in on you.
Take it on the go. When all else fails and if you have a laptop or tablet, try to work somewhere else. Many malls, coffee shops, and libraries have free wi-fi areas where you can connect to the Internet and work in relative peace. (This also requires having someone else watch the kids.)
What methods do you use to get work done at home?